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NOBOX Antibody, FITC Conjugated

NOBOX Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, NOBOX Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNOBOX
SpecificityThis is a highly specific antibody against NOBOX
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human NOBOX
Gene ID number135935
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 1% of all women are affected by POF, In addition, Missense mutations have been shown to cause nonsyndromic ovarian failure by disrupting the NOBOX proteins ability to bind to NOBOX DNA-binding element (NBE), NOBOX (newborn ovary homeobox gene), NOBOX expression in the ovary is oocyte specific, The cessation of ovarian function under the age of 40 years results in premature ovarian failure (POF) and is accompanied by amenorrhea, an ooctye-specific homeobox gene, and mutations in a few genes, and thereby inhibiting its regulation of Pou5f1 and GDF-9, but it shows expression in adult testis and pancreas as well, hypoestrogenism and elevated serum gonadotropin concentrations, including inhibin? fsh receptor and the LH/choriogonadotropin receptor have been linked to POF, is a critical protein involved in early folliculogenesis, several germ cell specific genes and downstream transcription factors are thought to play and important role in human oogenesis, Early ovarian folliculogenesis is characterized by the breakdown of germ cell clusters and formation of primordial follicles
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms OG2 Og2x
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNOBOX Conjugated
Short name FITC Conjugated, NOBOX Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, NOBOX (Antibody to)
Alternative techniqueantibodies
Identity 22448
Gene NOBOX
Long gene name NOBOX oogenesis homeobox
Synonyms name newborn ovary homeobox-encoding gene
Locus 7q35
Discovery year 2006-05-19
Entrez gene record 135935
Pubmed identfication 11804785 16597639
RefSeq identity XM_001134420
Classification PRD class homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000158051

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