Name : NOBOX Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5311719866
| Long name | FITC Conjugated, NOBOX Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NOBOX |
| Specificity | This is a highly specific antibody against NOBOX |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human NOBOX |
| Gene ID number | 135935 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | 1% of all women are affected by POF, In addition, Missense mutations have been shown to cause nonsyndromic ovarian failure by disrupting the NOBOX proteins ability to bind to NOBOX DNA-binding element (NBE), NOBOX (newborn ovary homeobox gene), NOBOX expression in the ovary is oocyte specific, The cessation of ovarian function under the age of 40 years results in premature ovarian failure (POF) and is accompanied by amenorrhea, an ooctye-specific homeobox gene, and mutations in a few genes, and thereby inhibiting its regulation of Pou5f1 and GDF-9, but it shows expression in adult testis and pancreas as well, hypoestrogenism and elevated serum gonadotropin concentrations, including inhibin? fsh receptor and the LH/choriogonadotropin receptor have been linked to POF, is a critical protein involved in early folliculogenesis, several germ cell specific genes and downstream transcription factors are thought to play and important role in human oogenesis, Early ovarian folliculogenesis is characterized by the breakdown of germ cell clusters and formation of primordial follicles |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | OG2 Og2x |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | NOBOX Conjugated |
| Short name | FITC Conjugated, NOBOX Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, NOBOX (Antibody to) |
| Alternative technique | antibodies |
| Identity | 22448 |
| Gene | NOBOX |
| Long gene name | NOBOX oogenesis homeobox |
| Synonyms name | newborn ovary homeobox-encoding gene |
| Locus | 7q35 |
| Discovery year | 2006-05-19 |
| Entrez gene record | 135935 |
| Pubmed identfication | 11804785 16597639 |
| RefSeq identity | XM_001134420 |
| Classification | PRD class homeoboxes and pseudogenes |
| Havana BLAST/BLAT | OTTHUMG00000158051 |