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NOMO1 Antibody, FITC Conjugated

NOMO1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, NOMO1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNOMO1
SpecificityThis is a highly specific antibody against NOMO1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human NOMO1
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background All three NOMO proteins share similar functions and have been difficult to characterize individually, NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), NOMO1 (Nodal modulator 1), NOMO2 and NOMO3, a heritable disorder of connective tissue, also known as PM5, and are rapidly degraded or stabilized by Nicalin, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6), is a 1, 222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa, Three highly similar proteins termed NOMO1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms PM5
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNOMO1 Conjugated
Short name FITC Conjugated, NOMO1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, NOMO1 (Antibody to)
Alternative techniqueantibodies
Identity 30060
Gene NOMO1
Long gene name NODAL modulator 1
Locus 16p13, 11
Discovery year 2004-09-10
GenBank acession X57398
Entrez gene record 23420
Pubmed identfication 1310294 15257293
Havana BLAST/BLAT OTTHUMG00000090541

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