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NOSTRIN Antibody

NOSTRIN Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNOSTRIN Primary Polyclonal Antibody
Also known asNOSTRIN PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNOSTRIN
SpecificityThis is a highly specific antibody against NOSTRIN
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NOSTRIN
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen It consists of an N-terminal Cdc15 domain with an FCH (Fes/CIP homology) region, It functions as an adaptor protein binding to caveolin-1 via an internal domain and NOS3 via its SH3 domain, NOSTRIN also interacts with Dynamin and N-WASP via its SH3 domain, NOSTRIN is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, NOSTRIN typically exists as a trimer, The NOS3 protein is responsible for the production of nitric oxide (NO), The translocation of NOS3 from the plasma membrane to intracellular vesicle-like structures diminishes NO production, a potent mediator in various biological processes, also known as endothelial nitric oxide synthase traffic inducer, forming a ternary complex which facilitates caveolar transport of NOS3, is a member of the Pombe Cdc15 homology (PCH) family of proteins, kidney and heart, lung, two coiled coil domains and a C-terminal SH3 domain, NOSTRIN (nitric oxide synthase trafficker isoform 1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BM247 homolog, DaIP2, MGC20702, NOSTN_HUMAN, Nitric oxide synthase traffic inducer, Nitric oxide synthase trafficker, Nostrin, RP23-431D4, eNOS-trafficking inducer, mDaIP2, 2, BM247
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNOSTRIN
Short nameNOSTRIN Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namenitric oxide synthase trafficker (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, DNA-templated and biological process this GO :0046209 and nitric oxide metabolic process and biological process this GO :0050999 and regulation of nitric-oxide synthase activity and biological process, NOSTRIN and IDBG-74325 and ENSG00000163072 and 115677, Nostrin and IDBG-175946 and ENSMUSG00000034738 and 329416, nuclei, protein binding, this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0045892 and negative regulation of transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, 17865 and IDBG-641032 and ENSBTAG00000010362 and 521834, nitric oxide synthase trafficker
Identity 20203
Gene NOSTRIN
Long gene name nitric oxide synthase trafficking
Synonyms gene name nitric oxide synthase trafficker
Synonyms MGC20702
Locus 2q24, 3
Discovery year 2003-01-06
GenBank acession AJ532842
Entrez gene record 115677
Pubmed identfication 12446846
RefSeq identity NM_052946
Classification F-BAR domain containing
Havana BLAST/BLAT OTTHUMG00000153990

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