Name : NOSTRIN Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN8131840550
| Long name | Cy7 Conjugated, NOSTRIN Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | NOSTRIN |
| Specificity | This is a highly specific antibody against NOSTRIN |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human NOSTRIN |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | It consists of an N-terminal Cdc15 domain with an FCH (Fes/CIP homology) region, It functions as an adaptor protein binding to caveolin-1 via an internal domain and NOS3 via its SH3 domain, NOSTRIN also interacts with Dynamin and N-WASP via its SH3 domain, NOSTRIN is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, NOSTRIN typically exists as a trimer, The NOS3 protein is responsible for the production of nitric oxide (NO), The translocation of NOS3 from the plasma membrane to intracellular vesicle-like structures diminishes NO production, a potent mediator in various biological processes, also known as endothelial nitric oxide synthase traffic inducer, forming a ternary complex which facilitates caveolar transport of NOS3, is a member of the Pombe Cdc15 homology (PCH) family of proteins, kidney and heart, lung, two coiled coil domains and a C-terminal SH3 domain, NOSTRIN (nitric oxide synthase trafficker isoform 1) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | MGC20702 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | NOSTRIN Conjugated |
| Short name | Conjugated, NOSTRIN Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, nitric oxide synthase trafficker (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, DNA-templated and biological process this GO :0046209 and nitric oxide metabolic process and biological process this GO :0050999 and regulation of nitric-oxide synthase activity and biological process, NOSTRIN and IDBG-74325 and ENSG00000163072 and 115677, Nostrin and IDBG-175946 and ENSMUSG00000034738 and 329416, nuclei, protein binding, this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0045892 and negative regulation of transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, 17865 and IDBG-641032 and ENSBTAG00000010362 and 521834, nitric oxide synthase trafficker |
| Identity | 20203 |
| Gene | NOSTRIN |
| Long gene name | nitric oxide synthase trafficking |
| Synonyms gene name | nitric oxide synthase trafficker |
| Locus | 2q24, 3 |
| Discovery year | 2003-01-06 |
| GenBank acession | AJ532842 |
| Entrez gene record | 115677 |
| Pubmed identfication | 12446846 |
| RefSeq identity | NM_052946 |
| Classification | F-BAR domain containing |
| Havana BLAST/BLAT | OTTHUMG00000153990 |