Name : Notch 2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6012593522
| Long name | Notch 2 Primary Polyclonal Antibody |
| Also known as | Notch 2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Notch 2 |
| Specificity | This is a highly specific antibody against Notch 2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1570-1620/2471 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Notch2 |
| Gene ID number | 4853 |
| Swiss Prot | Q04721 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Affects the implementation of differentiation, In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation, Involved in bone remodeling and homeostasis, Jagged2 and Delta1 to regulate cell-fate determination, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus, proliferation and apoptotic programs (By similarity), Functions as a receptor for membrane-bound ligands Jagged1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AGS2, HJCYS, NOTCH2, Neurogenic locus notch homolog protein 2, Notch 2, hN2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Notch 2 |
| Short name | Notch 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Notch 2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 31862 |
| Gene | NOTCH2NL |
| Long gene name | notch 2 N-terminal like |
| Synonyms gene name | Notch homolog 2 (Drosophila) N-terminal like |
| Synonyms | N2N |
| Locus | 1q21, 1 |
| Discovery year | 2004-12-02 |
| Entrez gene record | 388677 |
| Pubmed identfication | 14673143 |
| RefSeq identity | NM_203458 |
| Havana BLAST/BLAT | OTTHUMG00000013754 |