Name : Notch 2 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2159201439
| Long name | ALEXA FLUOR 488 Conjugated, Notch 2 Polyclonal Antibody |
| Also known as | Anti-Notch 2 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Notch 2 |
| Specificity | This is a highly specific antibody against Notch 2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1570-1620/2471 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Notch2 |
| Gene ID Number | 4853 |
| Swiss Prot | Q04721 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Affects the implementation of differentiation, In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation, Involved in bone remodeling and homeostasis, Jagged2 and Delta1 to regulate cell-fate determination, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus, proliferation and apoptotic programs (By similarity), Functions as a receptor for membrane-bound ligands Jagged1 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | N2N |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Notch 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Notch 2 |
| Short name | Notch 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Notch 2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 31862 |
| Gene | NOTCH2NL |
| Long gene name | notch 2 N-terminal like |
| Synonyms gene name | Notch homolog 2 (Drosophila) N-terminal like |
| Locus | 1q21, 1 |
| Discovery year | 2004-12-02 |
| Entrez gene record | 388677 |
| Pubmed identfication | 14673143 |
| RefSeq identity | NM_203458 |
| Havana BLAST/BLAT | OTTHUMG00000013754 |