Name : Notch3/4 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9108637697
| Long name | Notch3/4 Primary Polyclonal Antibody |
| Also known as | Notch3/4 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Notch3/4 |
| Specificity | This is a highly specific antibody against Notch3/4 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from mouse Notch3 |
| Gene ID number | 4854 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Defects in NOTCH3 are associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) (swissprot), It affects the implementation of differentiation, Jagged2 and Delta1 to regulate cell-fate determination, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus, proliferation and apoptotic programs, NOTCH3 functions as a receptor for membrane-bound ligands Jagged1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CADASIL, CASIL, Notch homolog 3, INT 3, INT3, MGC74442, NOTC4_HUMAN, NOTCH 3, NOTCH-3, NOTCH-4, NOTCH3, NOTCH4 protein, Neurogenic locus notch homolog protein 1, Neurogenic locus notch homolog protein 3, Neurogenic locus notch homolog protein 4, Notch 4 intracellular domain, Notch homolog 4, hNotch 4, hNotch4 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Notch3/4 |
| Short name | Notch3/4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Notch3/4 (Antibody to) |
| Alternative technique | antibodies |