Name : Notch3/4 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN1654739480
| Long name | Cy3 Conjugated, Notch3/4 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Notch3/4 |
| Specificity | This is a highly specific antibody against Notch3/4 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from mouse Notch3 |
| Gene ID number | 4854 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Defects in NOTCH3 are associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) (swissprot), It affects the implementation of differentiation, Jagged2 and Delta1 to regulate cell-fate determination, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus, proliferation and apoptotic programs, NOTCH3 functions as a receptor for membrane-bound ligands Jagged1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | CADASIL, CASIL, Notch homolog 3, INT 3, INT3, MGC74442, NOTC4_HUMAN, NOTCH 3, NOTCH-3, NOTCH-4, NOTCH3, NOTCH4 protein, Neurogenic locus notch homolog protein 1, Neurogenic locus notch homolog protein 3, Neurogenic locus notch homolog protein 4, Notch 4 intracellular domain, Notch homolog 4, hNotch 4, hNotch4 |
| Properties | 1 of the Notch3/4 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Notch3/4 Conjugated |
| Short name | Conjugated, Notch3/4 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, Notch3/4 (Antibody to) |
| Alternative technique | antibodies |