NOTCH3 (487CT6.9.2) Monoclonal Antibody

NOTCH3 (487CT6.9.2) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 211

Size 0.1ml

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Long name	2) Monoclonal Antibody, 9, NOTCH3 (487CT6
Also known as	2) Monoclonal Antibody, 9, NOTCH3 (487CT6
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	NOTCH3
Specificity	This is a highly specific antibody against NOTCH3
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	2, 487CT6, 9
Source	This NOTCH3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 2291-2321 amino acids from the C-terminal region of human NOTCH3
Gene ID number	4854
Swiss Prot	Q9UM47
Tested Applications	WB
Recommended dilutions	WB(1:100~250)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Affects the implementation of differentiation, Jagged2 and Delta1 to regulate cell-fate determination, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus, proliferation and apoptotic programs (By similarity), Functions as a receptor for membrane-bound ligands Jagged1
Purification method	This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	CADASIL, CADASIL1, CASIL, LMNS, NOTCH3, Neurogenic locus notch homolog protein 3, Notch 3, IMF2
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	2) Monoclonal, 9, NOTCH3 (487CT6
Short name	2) Monoclonal Antibody, 9, NOTCH3 (487CT6
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	2) monoclonal (Antibody to), 9, NOTCH3 (487CT6
Alternative technique	antibodies
Identity	7883
Gene	NOTCH3
Long gene name	notch 3
Synonyms gene	CADASIL
Synonyms gene name	Notch (Drosophila) homolog 3 Notch homolog 3 (Drosophila)
Synonyms	CASIL
Locus	19p13, 12
Discovery year	1994-07-04
GenBank acession	U97669
Entrez gene record	4854
Pubmed identfication	7835890
RefSeq identity	NM_000435
Classification	Ankyrin repeat domain containing
Havana BLAST/BLAT	OTTHUMG00000183217
Locus Specific Databases	NOTCH3 - CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical LOVD - Leiden Open Variation Database

NOTCH3 (487CT6.9.2) Monoclonal Antibody

NOTCH3 (487CT6.9.2) Monoclonal Antibody size: 0.1ml 211

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