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NOTCH3 Antibody

NOTCH3 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenNOTCH3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the NOTCH3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis NOTCH3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9UM47
PurityPurified
Description Homologues of the notch-ligands have also been identified in human, In Drosophilia, Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), but precise interactions between these ligands and the human notch homologues remains to be determined, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development, NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch
ImmunogenA portion of amino acids 2291-2321 from the human protein was used as the immunogen for this NOTCH3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NOTCH3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetNOTCH3
Short nameNOTCH3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNOTCH3 (Antibody to)
Alternative techniqueantibodies
Identity 5567
Gene IGHV1OR15-5
Long gene name immunoglobulin heavy variable 1/OR15-5 (non-functional)
Synonyms gene name immunoglobulin heavy variable 1/OR15-5 immunoglobulin heavy variable 1/OR15-5 pseudogene immunoglobulin heavy variable 1/OR15-5 (pseudogene)
Synonyms IGHV1/OR15-5
Locus 15q11, 2 not on reference assembly
Discovery year 2000-04-17
GenBank acession Z29633
Entrez gene record 100384884
RefSeq identity NG_016978
Classification Immunoglobulin heavy (IGH) orphons

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