Name : Noxa Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6686224096
| Long name | Noxa Primary Polyclonal Antibody |
| Also known as | Noxa PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Noxa |
| Specificity | This is a highly specific antibody against Noxa |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Noxa |
| Gene ID number | 5366 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity), Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1, Contributes to p53/TP53-dependent apoptosis after radiation exposure, Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria, Promotes proteasomal degradation of MCL1, Promotes activation of caspases and apoptosis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | APR, APR_HUMAN, Immediate early response protein APR, Immediate-early-response protein APR, PMA induced protein 1, PMA-induced protein 1, PMAIP1, Phorbol 12 myristate 13 acetate induced protein 1, Phorbol-12-myristate-13-acetate-induced protein 1, Protein Noxa, Adult T cell leukemia derived PMA responsive |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Noxa |
| Short name | Noxa Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Noxa (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9108 |
| Gene | PMAIP1 |
| Long gene name | phorbol-12-myristate-13-acetate-induced protein 1 |
| Synonyms | APR NOXA |
| Locus | 18q21, 32 |
| Discovery year | 1991-08-12 |
| GenBank acession | D90070 |
| Entrez gene record | 5366 |
| Pubmed identfication | 2398525 12879012 |
| RefSeq identity | NM_021127 |
| Classification | BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT | OTTHUMG00000132765 |