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NPC2/Niemann Pick C2 Antibody, ALEXA FLUOR 350

NPC2/Niemann Pick C2 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, NPC2/Niemann Pick C2 Polyclonal Antibody
Also known asAnti-NPC2/Niemann Pick C2 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNPC2/Niemann Pick C2
SpecificityThis is a highly specific antibody against NPC2/Niemann Pick C2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Niemann Pick C2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Mutations in the NPC2 gene may cause Nieman-Pick type C2 disease and frontal lobe atrophy (1, NPC2 regulates the lipid composition of sperm membranes during maturation in the epididymis(1, Nieman-Pick type C2 is a fatal hereditary disease characterized by defective lysosome release of cholesterol (3), The disease is caused by HE1 deficiency, This differentiates NPC2 from NPC1, a lysosmal protein proven to be undetectable in fibroblasts from NPC2 patients (3), as NPC1 has HE1 protein present (3), 2, 2), 2), 3 (1, 3), NPC2 is a secreted protein mapping against gene 14q24
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms HE1 NP-C2 EDDM1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetNPC2/Niemann Pick C2
Short nameNPC2/Niemann Pick C2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, NPC2/Niemann Pick complement component 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ARMD14 and CO2, C2 and IDBG-124824 and ENSG00000166278 and 101928623, C2 and IDBG-174547 and ENSMUSG00000024371 and 12263, C2 and IDBG-633680 and ENSBTAG00000007450 and 515440, Extracellular, classical pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0045087 and innate immune response and biological process this GO :2000427 and positive regulation of apoptotic cell clearance and biological process, protein binding, this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006508 and proteolysis and biological process this GO :0006956 and complement activation and biological process this GO :0006958 and complement activation, this GO :0003824: catalytic activity, this GO :0003824: catalytic activity and also this GO :0004252: serine-type endopeptidase activity and also this GO :0005515: protein binding, this GO :0004252: serine-type endopeptidase activity, this GO :0005515: protein binding, 717, complement component 2
Identity 14537
Gene NPC2
Long gene name NPC intracellular cholesterol transporter 2
Synonyms gene name Niemann-Pick disease, type C2
Synonyms name epididymal protein 1
Locus 14q24, 3
Discovery year 2001-05-11
GenBank acession X67698
Entrez gene record 10577
Pubmed identfication 8418812 11125141
RefSeq identity NM_006432
Havana BLAST/BLAT OTTHUMG00000171212

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