Filters

NPC2/Niemann Pick C2 Antibody, Cy5.5 Conjugated

NPC2/Niemann Pick C2 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, NPC2/Niemann Pick C2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNPC2/Niemann Pick C2
SpecificityThis is a highly specific antibody against NPC2/Niemann Pick C2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Niemann Pick C2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Mutations in the NPC2 gene may cause Nieman-Pick type C2 disease and frontal lobe atrophy (1, NPC2 regulates the lipid composition of sperm membranes during maturation in the epididymis(1, Nieman-Pick type C2 is a fatal hereditary disease characterized by defective lysosome release of cholesterol (3), The disease is caused by HE1 deficiency, This differentiates NPC2 from NPC1, a lysosmal protein proven to be undetectable in fibroblasts from NPC2 patients (3), as NPC1 has HE1 protein present (3), 2, 2), 2), 3 (1, 3), NPC2 is a secreted protein mapping against gene 14q24
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms HE1 NP-C2 EDDM1
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetNPC2/Niemann Pick C2 Conjugated
Short name Conjugated, NPC2/Niemann Pick C2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, NPC2/Niemann Pick complement component 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ARMD14 and CO2, C2 and IDBG-124824 and ENSG00000166278 and 101928623, C2 and IDBG-174547 and ENSMUSG00000024371 and 12263, C2 and IDBG-633680 and ENSBTAG00000007450 and 515440, Extracellular, classical pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0045087 and innate immune response and biological process this GO :2000427 and positive regulation of apoptotic cell clearance and biological process, protein binding, this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006508 and proteolysis and biological process this GO :0006956 and complement activation and biological process this GO :0006958 and complement activation, this GO :0003824: catalytic activity, this GO :0003824: catalytic activity and also this GO :0004252: serine-type endopeptidase activity and also this GO :0005515: protein binding, this GO :0004252: serine-type endopeptidase activity, this GO :0005515: protein binding, 717, complement component 2
Identity 14537
Gene NPC2
Long gene name NPC intracellular cholesterol transporter 2
Synonyms gene name Niemann-Pick disease, type C2
Synonyms name epididymal protein 1
Locus 14q24, 3
Discovery year 2001-05-11
GenBank acession X67698
Entrez gene record 10577
Pubmed identfication 8418812 11125141
RefSeq identity NM_006432
Havana BLAST/BLAT OTTHUMG00000171212

Similar products

Subscribe to our Newsletter