Filters

NR2C2/TAK1 Antibody

NR2C2/TAK1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNR2C2/TAK1 Primary Polyclonal Antibody
Also known asNR2C2/TAK1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNR2C2/TAK1
Specificity This antibody may have a minor secondary cross-reactivity towards NR2C1 in human and rat, based upon a non-sequential 77% sequence similarity over the immunogen range, This is a highly specific antibody against NR2C2/TAK1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range490-540/596
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NR2C2/TAK1
Gene ID number7182
Swiss ProtP49116
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activates transcriptional activity of LHCG, An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, Antagonist of PPARA-mediated transactivation, Appears to be important for neurodevelopmentally regulated behavior (By similarity), Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences, May regulate gene expression during the late phase of spermatogenesis, Plays a fundamental role in early embryonic development and embryonic stem cells, Required for normal spermatogenesis and cerebellum development, Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1, retinoid X, thyroid hormone receptor and estrogen receptor pathways, vitamin D3 receptor, Orphan nuclear receptor that can act as a repressor or activator of transcription
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NR2C2, Nuclear receptor subfamily 2 group C member 2, Orphan nuclear receptor TAK1, Orphan nuclear receptor TR4, TAK1, Testicular receptor 4, TR4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNR2C2/TAK1
Short nameNR2C2/TAK1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNR2C2/TAK1 (Antibody to)
Alternative techniqueantibodies
Identity 7972
Gene NR2C2
Long gene name nuclear receptor subfamily 2 group C member 2
Synonyms gene TR4
Synonyms gene name group C, member 2 , nuclear receptor subfamily 2
Synonyms TAK1 TR2R1 hTAK1
Locus 3p25, 1
Discovery year 1998-05-15
GenBank acession L27586
Entrez gene record 7182
Pubmed identfication 8661150 8016112
RefSeq identity NM_003298
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000129839

Similar products

Subscribe to our Newsletter