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NR2C2/TAK1 Antibody, Biotin Conjugated

NR2C2/TAK1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, NR2C2/TAK1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNR2C2/TAK1
Specificity This antibody may have a minor secondary cross-reactivity towards NR2C1 in human and rat, based upon a non-sequential 77% sequence similarity over the immunogen range, This is a highly specific antibody against NR2C2/TAK1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range490-540/596
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human NR2C2/TAK1
Gene ID number7182
Swiss ProtP49116
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activates transcriptional activity of LHCG, An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, Antagonist of PPARA-mediated transactivation, Appears to be important for neurodevelopmentally regulated behavior (By similarity), Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences, May regulate gene expression during the late phase of spermatogenesis, Plays a fundamental role in early embryonic development and embryonic stem cells, Required for normal spermatogenesis and cerebellum development, Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1, retinoid X, thyroid hormone receptor and estrogen receptor pathways, vitamin D3 receptor, Orphan nuclear receptor that can act as a repressor or activator of transcription
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms TAK1 TR2R1 hTAK1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNR2C2/TAK1 Conjugated
Short name Conjugated, NR2C2/TAK1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, NR2C2/TAK1 (Antibody to)
Alternative techniqueantibodies
Identity 7972
Gene NR2C2
Long gene name nuclear receptor subfamily 2 group C member 2
Synonyms gene TR4
Synonyms gene name group C, member 2 , nuclear receptor subfamily 2
Locus 3p25, 1
Discovery year 1998-05-15
GenBank acession L27586
Entrez gene record 7182
Pubmed identfication 8661150 8016112
RefSeq identity NM_003298
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000129839

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