Name : NR2E3 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6700540075
| Long name | NR2E3 Primary Polyclonal Antibody |
| Also known as | NR2E3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | NR2E3 |
| Specificity | This is a highly specific antibody against NR2E3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NR2E3 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Defects in this gene encoding for the protein, NR2E3 has a role in regulating the signaling pathway elemental to the photoreceptor cell function and in regulating pathways involved in embryonic development, NR2E3 is an eye specific nuclear protein found in the outer nuclear layer of the adult retina (where the nuclei of cone and rod photoreceptors are located), The proteins belonging to this family are characterized by discrete domains functioning in DNA and ligand binding, also known as NR2E3 or PNR, belongs to a large family of nuclear hormone receptor transcription factors, cause enhanced S cone syndrome, which localizes to chromosome 15q22, 32, Photoreceptor-specific nuclear receptor |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ESCS, NR2 E3, NR2E3_HUMAN, Nr2e3, Nuclear receptor subfamily 2 group E member 3, Photoreceptor specic nuclear receptor, Photoreceptor-specic nuclear receptor antibody PNR, RNR, RP37, Rd 7, Retina specic nuclear receptor, Retina-specic nuclear receptor, Retinal degeneration 7, Retinal degeneration 7, rd7, ESCS |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | NR2E3 |
| Short name | NR2E3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | NR2E3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7974 |
| Gene | NR2E3 |
| Long gene name | nuclear receptor subfamily 2 group E member 3 |
| Synonyms gene name | group E, member 3 , nuclear receptor subfamily 2 |
| Synonyms | PNR rd7 RP37 |
| Locus | 15q23 |
| Discovery year | 1999-09-16 |
| Entrez gene record | 10002 |
| Pubmed identfication | 10220376 |
| RefSeq identity | NM_014249 |
| Classification | Nuclear hormone receptors |
| Havana BLAST/BLAT | OTTHUMG00000172841 |
| Locus Specific Databases | Mutations of the Photoreceptor cell-specific Nuclear Receptor LOVD - Leiden Open Variation Database |