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NRSF/REST Antibody

NRSF/REST Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNRSF/REST Primary Polyclonal Antibody
Also known asNRSF/REST PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNRSF/REST
SpecificityThis is a highly specific antibody against NRSF/REST
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range400-450/1097
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NRSF
Gene ID number5978
Swiss ProtQ13127
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, Restricts the expression of neuronal genes by associating with two distinct corepressors, Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression, mSin3 and CoREST, thereby acting as a chromatin modifier, which in turn recruit histone deacetylase to the promoters of REST-regulated genes, Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NRSF, Neural-restrictive silencer factor, RE1-silencing transcription factor, REST, X2 box repressor, XBR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNRSF/REST
Short nameNRSF/REST Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNRSF/REST (Antibody to)
Alternative techniqueantibodies
Identity 9966
Gene REST
Long gene name RE1 silencing transcription factor
Synonyms gene name RE1-silencing transcription factor
Synonyms NRSF XBR
Synonyms name neuron-restrictive silencer factor
Locus 4q12
Discovery year 1996-04-12
GenBank acession U13879
Entrez gene record 5978
Pubmed identfication 7871435 7697725
RefSeq identity NM_005612
Havana BLAST/BLAT OTTHUMG00000128770

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