Filters

NSMAF Antibody, ALEXA FLUOR 647

NSMAF Antibody, ALEXA FLUOR 647 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 647 Conjugated, NSMAF Polyclonal Antibody
Also known asAnti-NSMAF PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNSMAF
SpecificityThis is a highly specific antibody against NSMAF
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NSMAF
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen FAN (for factor associated with neutral sphingomyelinase (N-SMase) activation) is an intermediate protein that interacts with TNF-R1 to initiate TNF signaling events, FAN binds to TNF-R1 at the cytoplasmic NSD (N-SMase activating domain), FAN contains four carboxy-terminal WD-repeat domains which appear to be involved in protein-protein interaction, N-SMase has been shown to be involved in TNF-induced Raf-1 activation (6), The FAN WD-repeats may mediate the interaction between FAN and TNF-R1 (5), The majority of TNF functions are primarily mediated through TNF-R1 (1, These receptors, are expressed on most cell types (1, designated TNF-R1 and TNF-R2, which results in the initiation of the N-SMase pathway (5), 2), 3), 4), Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated through two distinct cell surface receptors (1
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms FAN GRAMD5
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the NSMAF Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetNSMAF
Short nameNSMAF Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, NSMAF (Antibody to)
Alternative techniqueantibodies
Identity 8017
Gene NSMAF
Long gene name neutral sphingomyelinase activation associated factor
Synonyms gene name neutral sphingomyelinase (N-SMase) activation associated factor
Locus 8q12, 1
Discovery year 1998-11-04
GenBank acession X96586
Entrez gene record 8439
Pubmed identfication 8808629 10640829
RefSeq identity NM_003580
Classification BEACH domain containing GRAM domain containing WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000164352

Subscribe to our Newsletter