Filters

NSMAF Antibody, FITC Conjugated

NSMAF Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, NSMAF Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNSMAF
SpecificityThis is a highly specific antibody against NSMAF
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human NSMAF
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background FAN (for factor associated with neutral sphingomyelinase (N-SMase) activation) is an intermediate protein that interacts with TNF-R1 to initiate TNF signaling events, FAN binds to TNF-R1 at the cytoplasmic NSD (N-SMase activating domain), FAN contains four carboxy-terminal WD-repeat domains which appear to be involved in protein-protein interaction, N-SMase has been shown to be involved in TNF-induced Raf-1 activation (6), The FAN WD-repeats may mediate the interaction between FAN and TNF-R1 (5), The majority of TNF functions are primarily mediated through TNF-R1 (1, These receptors, are expressed on most cell types (1, designated TNF-R1 and TNF-R2, which results in the initiation of the N-SMase pathway (5), 2), 3), 4), Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated through two distinct cell surface receptors (1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FAN GRAMD5
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNSMAF Conjugated
Short name FITC Conjugated, NSMAF Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, NSMAF (Antibody to)
Alternative techniqueantibodies
Identity 8017
Gene NSMAF
Long gene name neutral sphingomyelinase activation associated factor
Synonyms gene name neutral sphingomyelinase (N-SMase) activation associated factor
Locus 8q12, 1
Discovery year 1998-11-04
GenBank acession X96586
Entrez gene record 8439
Pubmed identfication 8808629 10640829
RefSeq identity NM_003580
Classification BEACH domain containing GRAM domain containing WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000164352

Similar products

Subscribe to our Newsletter