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NSMase2 Antibody

NSMase2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNSMase2 Primary Polyclonal Antibody
Also known asNSMase2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNSMase2
SpecificityThis is a highly specific antibody against NSMase2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NSMase2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Expression of N-SMase2 is upregulated during the G0/G1 phases of the cell cycle and optimal N-SMase2 activity occurs at a slightly basic pH of 7, Localized to the membrane of the Golgi apparatus, N-SMase2 deficiency is the cause of chondrodysplasia, N-SMase2 functions to catalyze the hydrolysis of sphingomyelin to form ceramide and phosphocholineâ, N-SMase2 is enzymatically activated by unsaturated fatty acids and phosphatidylserine and, a genetic disorder characterized by impaired bone growth that leads to short stature, also known as NSMASE2 or SMPD3 (sphingomyelin phosphodiesterase 3), bowlegs and underdeveloped joints, is a ubiquitously expressed 655 amino acid member of the magnesium-dependent phosphohydrolase protein family, is involved in growth suppression and postnatal development, through regulation of ceramide synthesis, &euro, &rdquo, 5, N-SMase2 (neutral sphingomyelinase 2), two proteins that mediate cell growth arrest and apoptosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cca1, Confluent 3Y1 cell-associated protein 1, NSMA2_HUMAN, Neutral sphingomyelinase 2, Neutral sphingomyelinase II, Smpd3, Sphingomyelin phosphodiesterase 3, nSMase-2, nSMase2, neutral sphingomyelinase 2, N-SMase2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNSMase2
Short nameNSMase2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNSMase2 (Antibody to)
Alternative techniqueantibodies
Identity 14240
Gene SMPD3
Long gene name sphingomyelin phosphodiesterase 3
Synonyms gene name neutral membrane (neutral sphingomyelinase II) , sphingomyelin phosphodiesterase 3
Synonyms NSMASE2
Synonyms name neutral sphingomyelinase II
Locus 16q22, 1
Discovery year 2000-12-12
GenBank acession AJ250460
Entrez gene record 55512
Pubmed identfication 10823942
RefSeq identity NM_018667
Havana BLAST/BLAT OTTHUMG00000137559

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