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NSMase2 Antibody, ALEXA FLUOR 647

NSMase2 Antibody, ALEXA FLUOR 647 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, NSMase2 Polyclonal Antibody
Also known asAnti-NSMase2 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNSMase2
SpecificityThis is a highly specific antibody against NSMase2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NSMase2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Expression of N-SMase2 is upregulated during the G0/G1 phases of the cell cycle and optimal N-SMase2 activity occurs at a slightly basic pH of 7, Localized to the membrane of the Golgi apparatus, N-SMase2 deficiency is the cause of chondrodysplasia, N-SMase2 functions to catalyze the hydrolysis of sphingomyelin to form ceramide and phosphocholineâ, N-SMase2 is enzymatically activated by unsaturated fatty acids and phosphatidylserine and, a genetic disorder characterized by impaired bone growth that leads to short stature, also known as NSMASE2 or SMPD3 (sphingomyelin phosphodiesterase 3), bowlegs and underdeveloped joints, is a ubiquitously expressed 655 amino acid member of the magnesium-dependent phosphohydrolase protein family, is involved in growth suppression and postnatal development, through regulation of ceramide synthesis, &euro, &rdquo, 5, N-SMase2 (neutral sphingomyelinase 2), two proteins that mediate cell growth arrest and apoptosis
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms NSMASE2
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the NSMase2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetNSMase2
Short nameNSMase2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, NSMase2 (Antibody to)
Alternative techniqueantibodies
Identity 14240
Gene SMPD3
Long gene name sphingomyelin phosphodiesterase 3
Synonyms gene name neutral membrane (neutral sphingomyelinase II) , sphingomyelin phosphodiesterase 3
Synonyms name neutral sphingomyelinase II
Locus 16q22, 1
Discovery year 2000-12-12
GenBank acession AJ250460
Entrez gene record 55512
Pubmed identfication 10823942
RefSeq identity NM_018667
Havana BLAST/BLAT OTTHUMG00000137559

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