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NSP3 Antibody

NSP3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNSP3 Primary Polyclonal Antibody
Also known asNSP3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNSP3
SpecificityThis is a highly specific antibody against NSP3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NSP3
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen FAN (for factor associated with neutral sphingomyelinase (N-SMase) activation) is an intermediate protein that interacts with TNF-R1 to initiate TNF signaling events, FAN binds to TNF-R1 at the cytoplasmic NSD (N-SMase activating domain), FAN contains four carboxy-terminal WD-repeat domains which appear to be involved in protein-protein interaction, N-SMase has been shown to be involved in TNF-induced Raf-1 activation (6), The FAN WD-repeats may mediate the interaction between FAN and TNF-R1 (5), The majority of TNF functions are primarily mediated through TNF-R1 (1, These receptors, are expressed on most cell types (1, designated TNF-R1 and TNF-R2, which results in the initiation of the N-SMase pathway (5), 2), 3), 4), Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated through two distinct cell surface receptors (1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CHAT, FLJ39664, NSP 3, Novel SH2 containing protein 3, Novel SH2-containing protein 3, PRO34088, SH2 domain containing 3C, SH2 domain containing Eph receptor binding protein 1, SH2 domain containing protein 3C, SH2 domain-containing protein 3C, SH2D3C, SH2D3_HUMAN, Shep1, Cas/HEF1 associated signal transducer
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNSP3
Short nameNSP3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNSP3 (Antibody to)
Alternative techniqueantibodies
Identity 16884
Gene SH2D3C
Long gene name SH2 domain containing 3C
Synonyms gene name SH2 domain-containing 3C
Synonyms NSP3
Locus 9q34, 11
Discovery year 2001-11-19
GenBank acession AF124251
Entrez gene record 10044
Pubmed identfication 10187783
RefSeq identity NM_005489
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000020717

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