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NSP3 Antibody, Biotin Conjugated

NSP3 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, NSP3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNSP3
SpecificityThis is a highly specific antibody against NSP3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human NSP3
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background FAN (for factor associated with neutral sphingomyelinase (N-SMase) activation) is an intermediate protein that interacts with TNF-R1 to initiate TNF signaling events, FAN binds to TNF-R1 at the cytoplasmic NSD (N-SMase activating domain), FAN contains four carboxy-terminal WD-repeat domains which appear to be involved in protein-protein interaction, N-SMase has been shown to be involved in TNF-induced Raf-1 activation (6), The FAN WD-repeats may mediate the interaction between FAN and TNF-R1 (5), The majority of TNF functions are primarily mediated through TNF-R1 (1, These receptors, are expressed on most cell types (1, designated TNF-R1 and TNF-R2, which results in the initiation of the N-SMase pathway (5), 2), 3), 4), Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated through two distinct cell surface receptors (1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms NSP3
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNSP3 Conjugated
Short name Conjugated, NSP3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, NSP3 (Antibody to)
Alternative techniqueantibodies
Identity 16884
Gene SH2D3C
Long gene name SH2 domain containing 3C
Synonyms gene name SH2 domain-containing 3C
Locus 9q34, 11
Discovery year 2001-11-19
GenBank acession AF124251
Entrez gene record 10044
Pubmed identfication 10187783
RefSeq identity NM_005489
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000020717

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