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NTN3/Netrin-3 Antibody, ALEXA FLUOR 555

NTN3/Netrin-3 Antibody, ALEXA FLUOR 555 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 555 Conjugated, NTN3/Netrin-3 Polyclonal Antibody
Also known asAnti-NTN3/Netrin-3 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNTN3/Netrin-3
SpecificityThis is a highly specific antibody against NTN3/Netrin-3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NTN3/Netrin-3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen During peripheral nerve development, In axonal cells, In humans, Neogenin serves as the primary guidance receptor for netrin-3, Neogenin serves as the primary guidance receptor for netrin-3, Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity, Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, Netrin-3 proteins are associated with the axon fibers projecting from motor neurons and from neurons within sympathetic and sensory ganglia, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins as the cells are repelled, and, by the netrin gradient, high netrin-3 expression has been detected in mesenchymal cells, like netrin-1, rather than attracted, sensory ganglia and muscles, suggesting that netrin-3 may be involved in pathfinding and fasciculation of axon projection, the gene encoding for the netrin-3 protein is localized to chromosome 16p13, they can either attract or repel commissural axons at a distance, 3, Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetNTN3/Netrin-3
Short nameNTN3/Netrin-3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, NTN3/Netrin-3 (Antibody to)
Alternative techniqueantibodies
Identity 8030
Gene NTN3
Long gene name netrin 3
Synonyms gene NTN2L
Synonyms gene name netrin 2 (chicken)-like netrin 2-like (chicken)
Synonyms name Netrin-3
Locus 16p13, 3
Discovery year 1997-02-05
GenBank acession U86759
Entrez gene record 4917
Pubmed identfication 9143507 10366627
RefSeq identity NM_006181
Classification Netrins
Havana BLAST/BLAT OTTHUMG00000128867

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