NTN3/Netrin-3 Antibody, Biotin Conjugated

NTN3/Netrin-3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, NTN3/Netrin-3 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	NTN3/Netrin-3
Specificity	This is a highly specific antibody against NTN3/Netrin-3
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human NTN3/Netrin-3
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	During peripheral nerve development, In axonal cells, In humans, Neogenin serves as the primary guidance receptor for netrin-3, Neogenin serves as the primary guidance receptor for netrin-3, Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity, Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, Netrin-3 proteins are associated with the axon fibers projecting from motor neurons and from neurons within sympathetic and sensory ganglia, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins as the cells are repelled, and, by the netrin gradient, high netrin-3 expression has been detected in mesenchymal cells, like netrin-1, rather than attracted, sensory ganglia and muscles, suggesting that netrin-3 may be involved in pathfinding and fasciculation of axon projection, the gene encoding for the netrin-3 protein is localized to chromosome 16p13, they can either attract or repel commissural axons at a distance, 3, Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	NTN3/Netrin-3 Conjugated
Short name	Conjugated, NTN3/Netrin-3 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, NTN3/Netrin-3 (Antibody to)
Alternative technique	antibodies
Identity	8030
Gene	NTN3
Long gene name	netrin 3
Synonyms gene	NTN2L
Synonyms gene name	netrin 2 (chicken)-like netrin 2-like (chicken)
Synonyms name	Netrin-3
Locus	16p13, 3
Discovery year	1997-02-05
GenBank acession	U86759
Entrez gene record	4917
Pubmed identfication	9143507 10366627
RefSeq identity	NM_006181
Classification	Netrins
Havana BLAST/BLAT	OTTHUMG00000128867

NTN3/Netrin-3 Antibody, Biotin Conjugated

NTN3/Netrin-3 Antibody, Biotin Conjugated size: 0.1ml 333

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