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Nucleophosmin Antibody, ALEXA FLUOR 350

Nucleophosmin Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, Nucleophosmin Polyclonal Antibody
Also known asAnti-Nucleophosmin PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNucleophosmin
SpecificityThis is a highly specific antibody against Nucleophosmin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-50/259
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Nucleophosmin
Gene ID Number4869
Swiss ProtP06748
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts as a chaperonin for the core histones H3, Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids, Binds ribosome presumably to drive ribosome nuclear export, H2B and H4, In concert with BRCA2, May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules, Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation, Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication, Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA, and regulation of tumor suppressors p53/TP53 and ARF, cell proliferation, centrosome duplication, histone assembly, protein chaperoning, regulates centrosome duplication, Involved in diverse cellular processes such as ribosome biogenesis
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetNucleophosmin
Short nameNucleophosmin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, Nucleophosmin (Antibody to)
Alternative techniqueantibodies
Identity 7915
Gene NPM1P13
Long gene name nucleophosmin 1 pseudogene 13
Synonyms gene name nucleophosmin 1 (nucleolar phosphoprotein B23, numatrin) pseudogene 13
Locus 7p21, 1
Discovery year 1999-07-22
GenBank acession AC004994
Entrez gene record 10834
Havana BLAST/BLAT OTTHUMG00000152542

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