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NUMBL Antibody

NUMBL Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNUMBL Primary Polyclonal Antibody
Also known asNUMBL PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNUMBL
SpecificityThis is a highly specific antibody against NUMBL
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NUMBL
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CAG3A, CTG3a, Expressed at high levels in developing brain tissue, In mice, LNX1 and Notch 1, NBL, NUMBLIKE or TNRC23, NumbL (NUMB-like protein), NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, a signaling adapter protein with two protein-protein interaction domains, also known as Numb-R, deletion of the NumbL gene is associated with early embryonic death, including Eps15, is a 609 amino acid cytoplasmic protein that, is thought to play a role in cell fate, like NUMB, namely a phosphotyrosine-binding domain and a proline-rich SH3-binding region (PRR), neuronal cell fate decisions are directed by NUMB, possibly associating with Eps15 and Notch 1, suggesting an essential role for NumbL in early development, In Drosophila
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CAG3A, CTG 3a, CTG3a, NBL, NUMB Drosophilia Homolog Like, NUMB R, NUMBL, NUMBL_HUMAN, NUMBR, Numb homolog Drosophila like, Numb homolog like, Numb like protein, Numb-R, Numb-like protein, Numb-related protein, TNRC 23, TNRC23, CAG 3A
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNUMBL
Short nameNUMBL Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namenumb homolog (Drosophila)-like (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CAG3A and CTG3a and NBL and NUMB-R and NUMBLIKE and NUMBR and TNRC23, Cytoplasm, NUMBL and IDBG-52025 and ENSG00000105245 and 9253, NUMBL and IDBG-638153 and ENSBTAG00000019461 and 510973, Numbl and IDBG-160322 and ENSMUSG00000063160 and 18223, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007399 and nervous system development and biological process this GO :0007405 and neuroblast proliferation and biological process this GO :0007409 and axonogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019538 and protein metabolic process and biological process this GO :0021670 and lateral ventricle development and biological process this GO :0021849 and neuroblast division in subventricular zone and biological process this GO :0030900 and forebrain development and biological process this GO :0034332 and adherens junction organization and biological process this GO :0045087 and innate immune response and biological process this GO :0050769 and positive regulation of neurogenesis and biological process this GO :0050775 and positive regulation of dendrite morphogenesis and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, numb homolog (Drosophila)-like
Identity 8061
Gene NUMBL
Long gene name NUMB like, endocytic adaptor protein
Synonyms gene name numb (Drosophila) homolog-like
Synonyms NUMB-R CTG3a CAG3A TNRC23 NUMBR NUMBLIKE
Locus 19q13, 2
Discovery year 1999-03-12
GenBank acession AF015401
Entrez gene record 9253
Pubmed identfication 9225980 9303539
RefSeq identity NM_004756
Classification Trinucleotide repeat containing
Havana BLAST/BLAT OTTHUMG00000182627

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