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NUMBL Antibody, Cy7 Conjugated

NUMBL Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, NUMBL Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNUMBL
SpecificityThis is a highly specific antibody against NUMBL
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human NUMBL
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CAG3A, CTG3a, Expressed at high levels in developing brain tissue, In mice, LNX1 and Notch 1, NBL, NUMBLIKE or TNRC23, NumbL (NUMB-like protein), NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, a signaling adapter protein with two protein-protein interaction domains, also known as Numb-R, deletion of the NumbL gene is associated with early embryonic death, including Eps15, is a 609 amino acid cytoplasmic protein that, is thought to play a role in cell fate, like NUMB, namely a phosphotyrosine-binding domain and a proline-rich SH3-binding region (PRR), neuronal cell fate decisions are directed by NUMB, possibly associating with Eps15 and Notch 1, suggesting an essential role for NumbL in early development, In Drosophila
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms NUMB-R CTG3a CAG3A TNRC23 NUMBR NUMBLIKE
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetNUMBL Conjugated
Short name Conjugated, NUMBL Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, numb homolog (Drosophila)-like (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CAG3A and CTG3a and NBL and NUMB-R and NUMBLIKE and NUMBR and TNRC23, Cytoplasm, NUMBL and IDBG-52025 and ENSG00000105245 and 9253, NUMBL and IDBG-638153 and ENSBTAG00000019461 and 510973, Numbl and IDBG-160322 and ENSMUSG00000063160 and 18223, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007399 and nervous system development and biological process this GO :0007405 and neuroblast proliferation and biological process this GO :0007409 and axonogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019538 and protein metabolic process and biological process this GO :0021670 and lateral ventricle development and biological process this GO :0021849 and neuroblast division in subventricular zone and biological process this GO :0030900 and forebrain development and biological process this GO :0034332 and adherens junction organization and biological process this GO :0045087 and innate immune response and biological process this GO :0050769 and positive regulation of neurogenesis and biological process this GO :0050775 and positive regulation of dendrite morphogenesis and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, numb homolog (Drosophila)-like
Identity 8061
Gene NUMBL
Long gene name NUMB like, endocytic adaptor protein
Synonyms gene name numb (Drosophila) homolog-like
Locus 19q13, 2
Discovery year 1999-03-12
GenBank acession AF015401
Entrez gene record 9253
Pubmed identfication 9225980 9303539
RefSeq identity NM_004756
Classification Trinucleotide repeat containing
Havana BLAST/BLAT OTTHUMG00000182627

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