Name : NUR77 Antibody (NR4A1)
Supplier : NJS POLY
Price :199
SKU : GEN2034860845
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | NUR77 (NR4A1) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the NUR77 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This NUR77 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P22736 |
| Purity | Antigen affinity |
| Description | Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts, This protein acts as a nuclear transcription factor, Translocation of the protein from the nucleus to mitochondria induces apoptosis, NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily |
| Immunogen | A portion of amino acids 329-358 from the human protein was used as the immunogen for this NUR77 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NUR77 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | NUR77 (NR4A1) |
| Short name | NUR77 Antibody (NR4A1) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | family A, member 1), NUR77 (Antibody to) (nuclear receptor subfamily 4 |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010467 and gene expression and biological process this GO :0030522 and intracellular receptor signaling pathway and biological process this GO :0035767 and endothelial cell chemotaxis and biological process this GO :0035914 and skeletal muscle cell differentiation and biological process this GO :0035924 and cellular response to vascular endothelial growth factor stimulus and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043401 and steroid hormone mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0071310 and cellular response to organic substance and biological process, GFRP1 and HMR and N10 and NAK-1 and NGFIB and NP10 and NUR77 and TR3, NR4A1 and IDBG-33982 and ENSG00000123358 and 3164, NR4A1 and IDBG-632090 and ENSBTAG00000000507 and 528390, Nr4a1 and IDBG-185628 and ENSMUSG00000023034 and 15370, group A, member 1, nuclei, protein heterodimerization activity, this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003707 and steroid hormone receptor activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003707: steroid hormone receptor activity and also this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0042803: protein homodimerization activity and also this GO :0043565: sequence-specific DNA binding and also this GO :0046982: protein heterodimerization activity, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003707: steroid hormone receptor activity, this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0042803: protein homodimerization activity, this GO :0043565: sequence-specific DNA binding, this GO :0046982: protein heterodimerization activity, nuclear receptor subfamily 4 |
| Identity | 7980 |
| Gene | NR4A1 |
| Long gene name | nuclear receptor subfamily 4 group A member 1 |
| Synonyms gene | HMR GFRP1 |
| Synonyms gene name | group A, member 1 , nuclear receptor subfamily 4 |
| Synonyms | TR3 N10 NAK-1 NGFIB NUR77 |
| Locus | 12q13 |
| Discovery year | 1990-09-10 |
| GenBank acession | L13740 |
| Pubmed identfication | 2626032 |
| Classification | Nuclear hormone receptors |
| Havana BLAST/BLAT | OTTHUMG00000150393 |