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O-GlcNAc transferase Antibody

O-GlcNAc transferase Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameO-GlcNAc transferase Primary Polyclonal Antibody
Also known asO-GlcNAc transferase PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenO-GlcNAc transferase
SpecificityThis is a highly specific antibody against O-GlcNAc transferase
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human O-GlcNAc transferase
Gene ID number8473
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Both polypeptides are related, HeLa cells expressing O-GlcNAc transferase do not survive well during prolonged incubations, Immunofluorescence of human cells expressing rat O-GlcNAc transferase indicated that it is present in both the nucleus and cytosol, It exists as a heterotrimeric complex with two subunits of the same molecular mass and one shorter subunit, Mediates the O-glycosylation of MLL5 and HCFC1, O-GlcNAc transferase has been purified from rat liver, O-GlcNAc transferase is expressed as multiple transcripts that are present in different amounts in various human tissues, Promotes proteolytic maturation of HCFC1, Since both phosphorylation and glycosylation compete for similar serine or threonine residues, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects, suggesting that this protein may be toxic to the cells, the short subunit band is either a proteolytic product of the polypeptide or the product of an alternative translation start site, the two processes may compete for sites, with the highest levels of expression in pancreas, Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MGC22921, O GlcNAc, O GlcNAc transferase p110 subunit, O GlcNAc transferase subunit p110, O linked N acetylglucosamine GlcNAc transferase UDP N acetylglucosamine:polypeptide N acetylglucosaminyl transferase, O linked N acetylglucosamine transferase 110 kDa subunit, O-GlcNAc transferase, O-GlcNAc transferase subunit p110, O-Linked N-Acetylglucosamine Transferase, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT, OGT1_HUMAN, UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, Uridinediphospho N acetylglucosamine:polypeptide beta N acetylglucosaminyl transferase, HRNT1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetO-GlcNAc transferase
Short nameO-GlcNAc transferase Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameO-GlcNAc transferase (Antibody to)
Alternative techniqueantibodies
Identity 8127
Gene OGT
Long gene name O-linked N-acetylglucosamine (GlcNAc) transferase
Synonyms gene name O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
Synonyms O-GLCNAC HRNT1 MGC22921 FLJ23071
Synonyms name UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase
Locus Xq13, 1
Discovery year 1998-12-03
GenBank acession U77413
Entrez gene record 8473
Pubmed identfication 9083068
RefSeq identity NM_003605 NM_181672
Classification O-linked N-acetylglucosaminyltransferases Tetratricopeptide repeat domain containing
Havana BLAST/BLAT OTTHUMG00000033316
Locus Specific Databases Mental Retardation database

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