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OPA1 Antibody, FITC Conjugated

OPA1 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, OPA1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenOPA1
SpecificityThis is a highly specific antibody against OPA1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range680-725/960
Subcellular locationMitochondrion
SourceKLH conjugated synthetic peptide derived from human OPA1
Gene ID number84692
Swiss ProtQ8NEL0
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Defects in OPA1 are a cause of optic atrophy type 1, OPA1 is mostly expressed in retina but can also be expressed in brain, The OPA1 gene has been localized to 3q29, The gene is targeted to mitochondria and is involved in mitochondrial biogenesis, heart and skeletal muscle, testis, OPA1 is a 120kDa protein belonging to the dynamin family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms NTG KIAA0567 FLJ12460 NPG MGM1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetOPA1 Conjugated
Short name FITC Conjugated, OPA1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, optic atrophy 1 (autosomal dominant) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target GTP binding, OPA1 and IDBG-634327 and ENSBTAG00000019514 and 524142, OPA1 and IDBG-70072 and ENSG00000198836 and 4976, Opa1 and IDBG-151468 and ENSMUSG00000038084 and 74143, Plasma membranes, largeG and MGM1 and NPG and NTG, this GO :0000266 and mitochondrial fission and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0001843 and neural tube closure and biological process this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007007 and inner mitochondrial membrane organization and biological process this GO :0007601 and visual perception and biological process this GO :0008053 and mitochondrial fusion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019896 and axon transport of mitochondrion and biological process this GO :0030061 and mitochondrial crista and cellular component this GO :0030425 and dendrite and cellular component this GO :0090201 and negative regulation of release of cytochrome c from mitochondria and biological process this GO :0090398 and cellular senescence and biological process this GO :2001243 and negative regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0003924: GTPase activity and also this GO :0005515: protein binding and also this GO :0005525: GTP binding, this GO :0003924: GTPase activity, this GO :0005515: protein binding, this GO :0005525: GTP binding, optic atrophy 1 (autosomal dominant)
Identity 8140
Gene OPA1
Long gene name OPA1, mitochondrial dynamin like GTPase
Synonyms gene name optic atrophy 1 (autosomal dominant)
Synonyms name mitochondrial , mitochondrial dynamin-like GTPase dynamin-like guanosine triphosphatase Dynamin-like 120 kDa protein
Locus 3q29
Discovery year 1987-09-11
GenBank acession AB011139
Entrez gene record 4976
Pubmed identfication 9490303
RefSeq identity NM_130837
Havana BLAST/BLAT OTTHUMG00000149897
Locus Specific Databases Mutations of the Optic Atrophy 1 Gene LRG_337

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