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OPA1 Antibody (form S1)

OPA1 Antibody (form S1) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenOPA1 (form S1)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the OPA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis OPA1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O60313
PurityAntigen affinity
Description May form a diffusion barrier for proteins stored in mitochondrial cristae, Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space, Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis
Immunogen form S1, This OPA1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 895-929 amino acids from the C-terminal region of human OPA1
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the OPA1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetOPA1 (form S1)
Short nameOPA1 Antibody (form S1)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameoptic atrophy 1 (autosomal dominant) (Antibody to) (form S1)
Alternative techniqueantibodies
Alternative to gene target GTP binding, OPA1 and IDBG-634327 and ENSBTAG00000019514 and 524142, OPA1 and IDBG-70072 and ENSG00000198836 and 4976, Opa1 and IDBG-151468 and ENSMUSG00000038084 and 74143, Plasma membranes, largeG and MGM1 and NPG and NTG, this GO :0000266 and mitochondrial fission and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0001843 and neural tube closure and biological process this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007007 and inner mitochondrial membrane organization and biological process this GO :0007601 and visual perception and biological process this GO :0008053 and mitochondrial fusion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019896 and axon transport of mitochondrion and biological process this GO :0030061 and mitochondrial crista and cellular component this GO :0030425 and dendrite and cellular component this GO :0090201 and negative regulation of release of cytochrome c from mitochondria and biological process this GO :0090398 and cellular senescence and biological process this GO :2001243 and negative regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0003924: GTPase activity and also this GO :0005515: protein binding and also this GO :0005525: GTP binding, this GO :0003924: GTPase activity, this GO :0005515: protein binding, this GO :0005525: GTP binding, optic atrophy 1 (autosomal dominant)
Identity 8140
Gene OPA1
Long gene name OPA1, mitochondrial dynamin like GTPase
Synonyms gene name optic atrophy 1 (autosomal dominant)
Synonyms NTG KIAA0567 FLJ12460 NPG MGM1
Synonyms name mitochondrial , mitochondrial dynamin-like GTPase dynamin-like guanosine triphosphatase Dynamin-like 120 kDa protein
Locus 3q29
Discovery year 1987-09-11
GenBank acession AB011139
Entrez gene record 4976
Pubmed identfication 9490303
RefSeq identity NM_130837
Havana BLAST/BLAT OTTHUMG00000149897
Locus Specific Databases Mutations of the Optic Atrophy 1 Gene LRG_337

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