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OPG Antibody

OPG Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameOPG Primary Polyclonal Antibody
Also known asOPG PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenOPG
SpecificityThis is a highly specific antibody against OPG
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range235-280/401
Subcellular locationSecreted
SourceKLH conjugated synthetic peptide derived from mouse OPG
Gene ID number18383
Swiss ProtO08712
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B, Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro, May act as decoy receptor for TNFSF1/TRAIL and protect against apoptosis, May also play a role in preventing arterial calcification, TNFSF1/TRAIL binding blocks the inhibition of osteoclastogenesis, Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names OCIF, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TR1, Tnfrsf11b, Tumor necrosis factor receptor superfamily member 11B, Opg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetOPG
Short nameOPG Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameOPG (Antibody to)
Alternative techniqueantibodies
Identity 11909
Gene TNFRSF11B
Long gene name TNF receptor superfamily member 11b
Synonyms gene OPG
Synonyms gene name member 11b , osteoprotegerin tumor necrosis factor receptor superfamily
Synonyms OCIF TR1
Locus 8q24, 12
Discovery year 1997-09-05
GenBank acession U94332
Entrez gene record 4982
Pubmed identfication 9108485
Classification Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000164969

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