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Optineurin Antibody, Biotin Conjugated

Optineurin Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Optineurin Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenOptineurin
SpecificityThis is a highly specific antibody against Optineurin
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range350-400/577
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human Optineurin
Gene ID number10133
Swiss ProtQ96CV9
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Mouse, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family, Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation, May act by regulating membrane trafficking and cellular morphogenesis via a complex that contains Rab8 and hungtingtin (HD), May constitute a cellular target for adenovirus E3 14, Mediates the interaction of Rab8 with the probable GTPase-activating protein TBC1D17 during Rab8-mediated endocytic trafficking, Negatively regulates the induction of IFNB in response to RNA virus infection, Plays a neuroprotective role in the eye and optic nerve, Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death, an inhibitor of TNF-alpha functions, and appears to function in the same pathway as SQSTM1 and CALCOCO2/NDP52, in exocytosis, in membrane trafficking, regulates Rab8 recruitnment to tubules emanating from the endocytic recycling compartment, such as cytoplasmic Salmonella enterica, such as of transferrin receptor (TFRC/TfR), targets ubiquitin-coated bacteria (xenophagy), thereby affecting cell death, through its interaction with myosin VI and Rab8, 7, Plays an important role in the maintenance of the Golgi complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms ALS12, E3-14, FIP-2, FIP2, GLC1E, HIP-7, HIP7, HYPL, Huntingtin yeast partner L, Huntingtin-interacting protein 7, Huntingtin-interacting protein L, NEMO-related protein, OPTN, Optic neuropathy-inducing protein, Optineurin, TFIIIA-INTP, Transcription factor IIIA-interacting protein, 7K-interacting protein, NRP
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetOptineurin Conjugated
Short name Conjugated, Optineurin Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Optineurin (Antibody to)
Alternative techniqueantibodies

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