Name : ORC1L Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2666827103
| Long name | ALEXA FLUOR 555 Conjugated, ORC1L Polyclonal Antibody |
| Also known as | Anti-ORC1L PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ORC1L |
| Specificity | This is a highly specific antibody against ORC1L |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ORC1L/ORC1 |
| Gene ID Number | 4998 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1), Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1), ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle, ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7, ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5, The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8), however, only ORC2 remains stably bound to chromatin (3, such as the testis (2), which trigger initiation (1), 4), 6), 8), The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | HSORC1 PARC1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | ORC1L |
| Short name | ORC1L Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, ORC1L (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8487 |
| Gene | ORC1 |
| Long gene name | origin recognition complex subunit 1 |
| Synonyms gene | ORC1L |
| Synonyms gene name | cerevisiae) origin recognition complex, origin recognition complex, subunit 1 , subunit 1 (yeast homolog)-like origin recognition complex, subunit 1 homolog (S, subunit 1-like (yeast) origin recognition complex |
| Synonyms name | S, cerevisiae, homolog-like origin recognition complex 1 replication control protein 1 , origin recognition complex, subunit 1 |
| Locus | 1p32, 3 |
| Discovery year | 1997-06-24 |
| Entrez gene record | 4998 |
| Pubmed identfication | 8884289 |
| RefSeq identity | NM_004153 |
| Classification | AAA ATPases Origin recognition complex |
| Havana BLAST/BLAT | OTTHUMG00000008104 |