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ORC1L Antibody, Biotin Conjugated

ORC1L Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, ORC1L Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenORC1L
SpecificityThis is a highly specific antibody against ORC1L
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ORC1L/ORC1
Gene ID number4998
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1), Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1), ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle, ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7, ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5, The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8), however, only ORC2 remains stably bound to chromatin (3, such as the testis (2), which trigger initiation (1), 4), 6), 8), The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms HSORC1 PARC1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetORC1L Conjugated
Short name Conjugated, ORC1L Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ORC1L (Antibody to)
Alternative techniqueantibodies
Identity 8487
Gene ORC1
Long gene name origin recognition complex subunit 1
Synonyms gene ORC1L
Synonyms gene name cerevisiae) origin recognition complex, origin recognition complex, subunit 1 , subunit 1 (yeast homolog)-like origin recognition complex, subunit 1 homolog (S, subunit 1-like (yeast) origin recognition complex
Synonyms name S, cerevisiae, homolog-like origin recognition complex 1 replication control protein 1 , origin recognition complex, subunit 1
Locus 1p32, 3
Discovery year 1997-06-24
Entrez gene record 4998
Pubmed identfication 8884289
RefSeq identity NM_004153
Classification AAA ATPases Origin recognition complex
Havana BLAST/BLAT OTTHUMG00000008104

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