Name : ORC1L Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN4625630792
| Long name | Cy3 Conjugated, ORC1L Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ORC1L |
| Specificity | This is a highly specific antibody against ORC1L |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human ORC1L/ORC1 |
| Gene ID number | 4998 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1), Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1), ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle, ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7, ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5, The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8), however, only ORC2 remains stably bound to chromatin (3, such as the testis (2), which trigger initiation (1), 4), 6), 8), The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | HSORC1 PARC1 |
| Properties | 1 of the ORC1L Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ORC1L Conjugated |
| Short name | Conjugated, ORC1L Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, ORC1L (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8487 |
| Gene | ORC1 |
| Long gene name | origin recognition complex subunit 1 |
| Synonyms gene | ORC1L |
| Synonyms gene name | cerevisiae) origin recognition complex, origin recognition complex, subunit 1 , subunit 1 (yeast homolog)-like origin recognition complex, subunit 1 homolog (S, subunit 1-like (yeast) origin recognition complex |
| Synonyms name | S, cerevisiae, homolog-like origin recognition complex 1 replication control protein 1 , origin recognition complex, subunit 1 |
| Locus | 1p32, 3 |
| Discovery year | 1997-06-24 |
| Entrez gene record | 4998 |
| Pubmed identfication | 8884289 |
| RefSeq identity | NM_004153 |
| Classification | AAA ATPases Origin recognition complex |
| Havana BLAST/BLAT | OTTHUMG00000008104 |