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OSCAR Antibody

OSCAR Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenOSCAR
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the OSCAR antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis OSCAR antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q8IYS5
PurityAntigen affinity
Description Different from the other LRC members, Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts, OSCAR may be an important bone-specific regulator of osteoclast differentiation, This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses, Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis
ImmunogenA portion of amino acids 205-231 from the human protein was used as the immunogen for this OSCAR antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the OSCAR antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetOSCAR
Short nameOSCAR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name immunoglobulin-like receptor (Antibody to), osteoclast associated
Alternative techniqueantibodies
Alternative to gene target OSCAR and IDBG-642249 and ENSBTAG00000001051 and 100336423, OSCAR and IDBG-67991 and ENSG00000170909 and 126014, Oscar and IDBG-135635 and ENSMUSG00000054594 and 232790, Plasma membranes, immunoglobulin-like receptor, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, osteoclast associated
Identity 29960
Gene OSCAR
Long gene name immunoglobulin-like receptor , osteoclast associated
Locus 19q13, 42
Discovery year 2007-06-21
GenBank acession AK130199
Entrez gene record 126014
Pubmed identfication 11805147
RefSeq identity NM_133169
Classification Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000064966

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