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OST-beta Antibody

OST-beta Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameOST-beta Primary Polyclonal Antibody
Also known asOST-beta PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenOST-beta
SpecificityThis is a highly specific antibody against OST-beta
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OST-beta
Gene ID number123264
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor), OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane, OST Beta is present at highest levels in ileum, This genetic regulation suggests that in response to changes in intracellular bile acid levels, Though widely expressed, bile acids adjust the rate of their own efflux from enterocytes, kidney and adrenal gland, liver, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus, testis, The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names OST-beta, OSTB, OSTB_HUMAN, Organic solute transporter subunit beta, Ost beta, Ostbeta, organic solute transporter beta Ostbeta
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetOST-beta
Short nameOST-beta Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameOST-b (Antibody to)
Alternative techniqueantibodies
Identity 2728
Gene DDOST
Long gene name dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Synonyms gene name dolichyl-diphosphooligosaccharide-protein glycosyltransferase
Synonyms OST KIAA0115 OST48 WBP1
Synonyms name oligosaccharyltransferase subunit 48 advanced glycation end-product receptor 1
Locus 1p36, 12
Discovery year 1997-12-23
GenBank acession D29643
Entrez gene record 1650
Pubmed identfication 9367678
RefSeq identity NM_005216
Classification Oligosaccharyltransferase complex subunits
Havana BLAST/BLAT OTTHUMG00000002844

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