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OST-beta Antibody, ALEXA FLUOR 555

OST-beta Antibody, ALEXA FLUOR 555 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 555 Conjugated, OST-beta Polyclonal Antibody
Also known asAnti-OST-beta PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenOST-beta
SpecificityThis is a highly specific antibody against OST-beta
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OST-beta
Gene ID Number123264
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor), OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane, OST Beta is present at highest levels in ileum, This genetic regulation suggests that in response to changes in intracellular bile acid levels, Though widely expressed, bile acids adjust the rate of their own efflux from enterocytes, kidney and adrenal gland, liver, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus, testis, The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms OST KIAA0115 OST48 WBP1
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetOST-beta
Short nameOST-beta Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, OST-b (Antibody to)
Alternative techniqueantibodies
Identity 2728
Gene DDOST
Long gene name dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Synonyms gene name dolichyl-diphosphooligosaccharide-protein glycosyltransferase
Synonyms name oligosaccharyltransferase subunit 48 advanced glycation end-product receptor 1
Locus 1p36, 12
Discovery year 1997-12-23
GenBank acession D29643
Entrez gene record 1650
Pubmed identfication 9367678
RefSeq identity NM_005216
Classification Oligosaccharyltransferase complex subunits
Havana BLAST/BLAT OTTHUMG00000002844

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