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OST-beta Antibody, FITC Conjugated

OST-beta Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, OST-beta Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenOST-beta
SpecificityThis is a highly specific antibody against OST-beta
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human OST-beta
Gene ID number123264
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor), OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane, OST Beta is present at highest levels in ileum, This genetic regulation suggests that in response to changes in intracellular bile acid levels, Though widely expressed, bile acids adjust the rate of their own efflux from enterocytes, kidney and adrenal gland, liver, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus, testis, The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms OST KIAA0115 OST48 WBP1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetOST-beta Conjugated
Short name FITC Conjugated, OST-beta Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, OST-b (Antibody to)
Alternative techniqueantibodies
Identity 2728
Gene DDOST
Long gene name dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Synonyms gene name dolichyl-diphosphooligosaccharide-protein glycosyltransferase
Synonyms name oligosaccharyltransferase subunit 48 advanced glycation end-product receptor 1
Locus 1p36, 12
Discovery year 1997-12-23
GenBank acession D29643
Entrez gene record 1650
Pubmed identfication 9367678
RefSeq identity NM_005216
Classification Oligosaccharyltransferase complex subunits
Havana BLAST/BLAT OTTHUMG00000002844

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