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OSTM1 Antibody, FITC Conjugated

OSTM1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, OSTM1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenOSTM1
SpecificityThis is a highly specific antibody against OSTM1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range32-88/334
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human OSTM1
Gene ID number28962
Swiss ProtQ86WC4
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ARO is suggested to be caused by mutations in the OSTM1 gene, Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, also known as gl (gray-lethal) or HSPC019, and a benign autosomal dominant form occurring in adolescence or adulthood, due to defective resorption of immature bone, infancy, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen, or childhood, which is responsible for a coat color defect in mice, OSTM1 (osteopetrosis associated transmembrane protein 1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms HSPC019 GL
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetOSTM1 Conjugated
Short name FITC Conjugated, OSTM1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, OSTM1 (Antibody to)
Alternative techniqueantibodies
Identity 21652
Gene OSTM1
Long gene name osteopetrosis associated transmembrane protein 1
Synonyms name CLCN7 accessory beta subunit
Locus 6q21
Discovery year 2003-10-06
GenBank acession AF533891
Entrez gene record 28962
Pubmed identfication 12627228 21527911
RefSeq identity NM_014028
Havana BLAST/BLAT OTTHUMG00000015317

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