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OTC Antibody

OTC Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameOTC Primary Polyclonal Antibody
Also known asOTC PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenOTC
SpecificityThis is a highly specific antibody against OTC
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range40-90/354
Subcellular locationMitochondrion
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTC
Gene ID number5009
Swiss ProtP00480
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Heterozygous females are either asymptomatic or express orotic aciduria spontaneously or after protein intake, Mutations with no residual enzyme activity are always expressed in hemizygote males by a very severe neonatal hyperammonemic coma that generally proves to be fatal, OTCD is an X-linked disorder of the urea cycle which causes a form of hyperammonemia, The arbitrary classification of patients into the 'neonatal' group (clinical hyperammonemia in the first few days of life) and 'late' onset (clinical presentation after the neonatal period) has been used to differentiate severe from mild forms, The disorder is treatable with supplemental dietary arginine and low protein diet, Defects in OTC are the cause of ornithine carbamoyltransferase deficiency (OTCD) [MIM:311250]
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names OTC, OTCase, Ornithine carbamoyltransferase, Ornithine transcarbamylase, mitochondrial, OCTD
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetOTC
Short nameOTC Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameOTC (Antibody to)
Alternative techniqueantibodies
Identity 8512
Gene OTC
Long gene name ornithine carbamoyltransferase
Locus Xp11, 4
Discovery year 2001-06-22
GenBank acession K02100
Entrez gene record 5009
Havana BLAST/BLAT OTTHUMG00000022727
Locus Specific Databases OTC - Ornithine transcarbamylase deficiency Mental Retardation database LOVD - Leiden Open Variation Database

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