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OTOA/DFNB22 Antibody

OTOA/DFNB22 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameOTOA/DFNB22 Primary Polyclonal Antibody
Also known asOTOA/DFNB22 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenOTOA/DFNB22
SpecificityThis is a highly specific antibody against OTOA/DFNB22
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTOA/DFNB22
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CT108 or DFNB22, Existing as three alternatively spliced isoforms, Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells, Sensorineural deafness results from damage to the neural receptors of the inner ear, also known as OTOA, is a 1, otoancorin is encoded by a gene located on human chromosome 16p12, otoancorin is suggested to act as an adhesion molecule, the nerve pathways to the brain or the area of the brain that receives sound information, which is a form of sensorineural hearing loss, 153 amino acid protein belonging to the stereocilin family, 2, Otoancorin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CT108, DFNB22, Deafness, OTOA, OTOAN_HUMAN, Otoancorin, autosomal recessive 22, Cancer/testis antigen 108
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetOTOA/DFNB22
Short nameOTOA/DFNB22 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameOTOA/DFNB22 (Antibody to)
Alternative techniqueantibodies
Identity 16378
Gene OTOA
Long gene name otoancorin
Synonyms gene DFNB22
Synonyms gene name autosomal recessive 22 , deafness
Synonyms CT108
Synonyms name cancer/testis antigen 108
Locus 16p12, 2
Discovery year 2002-07-05
GenBank acession AK057335
Entrez gene record 146183
Pubmed identfication 11972037 19088187
Classification Deafness associated genes
Havana BLAST/BLAT OTTHUMG00000090721

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