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OTOA/DFNB22 Antibody, Biotin Conjugated

OTOA/DFNB22 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, OTOA/DFNB22 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenOTOA/DFNB22
SpecificityThis is a highly specific antibody against OTOA/DFNB22
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human OTOA/DFNB22
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CT108 or DFNB22, Existing as three alternatively spliced isoforms, Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells, Sensorineural deafness results from damage to the neural receptors of the inner ear, also known as OTOA, is a 1, otoancorin is encoded by a gene located on human chromosome 16p12, otoancorin is suggested to act as an adhesion molecule, the nerve pathways to the brain or the area of the brain that receives sound information, which is a form of sensorineural hearing loss, 153 amino acid protein belonging to the stereocilin family, 2, Otoancorin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms CT108
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetOTOA/DFNB22 Conjugated
Short name Conjugated, OTOA/DFNB22 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, OTOA/DFNB22 (Antibody to)
Alternative techniqueantibodies
Identity 16378
Gene OTOA
Long gene name otoancorin
Synonyms gene DFNB22
Synonyms gene name autosomal recessive 22 , deafness
Synonyms name cancer/testis antigen 108
Locus 16p12, 2
Discovery year 2002-07-05
GenBank acession AK057335
Entrez gene record 146183
Pubmed identfication 11972037 19088187
Classification Deafness associated genes
Havana BLAST/BLAT OTTHUMG00000090721

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