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OTOA/DFNB22 Antibody, FITC Conjugated

OTOA/DFNB22 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, OTOA/DFNB22 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenOTOA/DFNB22
SpecificityThis is a highly specific antibody against OTOA/DFNB22
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human OTOA/DFNB22
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CT108 or DFNB22, Existing as three alternatively spliced isoforms, Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells, Sensorineural deafness results from damage to the neural receptors of the inner ear, also known as OTOA, is a 1, otoancorin is encoded by a gene located on human chromosome 16p12, otoancorin is suggested to act as an adhesion molecule, the nerve pathways to the brain or the area of the brain that receives sound information, which is a form of sensorineural hearing loss, 153 amino acid protein belonging to the stereocilin family, 2, Otoancorin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CT108
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetOTOA/DFNB22 Conjugated
Short name FITC Conjugated, OTOA/DFNB22 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, OTOA/DFNB22 (Antibody to)
Alternative techniqueantibodies
Identity 16378
Gene OTOA
Long gene name otoancorin
Synonyms gene DFNB22
Synonyms gene name autosomal recessive 22 , deafness
Synonyms name cancer/testis antigen 108
Locus 16p12, 2
Discovery year 2002-07-05
GenBank acession AK057335
Entrez gene record 146183
Pubmed identfication 11972037 19088187
Classification Deafness associated genes
Havana BLAST/BLAT OTTHUMG00000090721

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