Name : OTP Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2888795077
| Long name | OTP Primary Polyclonal Antibody |
| Also known as | OTP PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | OTP |
| Specificity | This is a highly specific antibody against OTP |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTP |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | At early embryonic stages in mice, Containing a homeobox DNA-binding domain and a OAR domain, OTP (orthopedia homeobox) is a 325 amino acid nuclear protein belonging to the paired homeobox family and Bicoid subfamily, OTP is expressed in neurons, OTP is highly conserved in evolution and is encoded by a gene located on human chromosome 5, OTP is suggested to be involved in the differentiation of hypothalamic neuroendocrine cells, anterior periventricular (aPV) and arcuate (ARN) nuclei, indicating a potential role for OTP as an upstream regulator of SIM2, supraoptic (SON), the expression of SIM2 is downregulated in the absence of OTP, which contains 181 million base pairs and comprises nearly 6% of the human genome, which give rise to the paraventricular (PVN), Homeodomain (HD) genes are helix-turn-helix transcription factors that play key roles in the specification of cell fates |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | OTP_HUMAN, orthopedia homeobox, orthopedia homolog, MGC3161 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | OTP |
| Short name | OTP Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | OTP (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8518 |
| Gene | OTP |
| Long gene name | orthopedia homeobox |
| Synonyms gene name | orthopedia homolog (Drosophila) |
| Locus | 5q14, 1 |
| Discovery year | 1999-02-09 |
| Entrez gene record | 23440 |
| Pubmed identfication | 10458915 |
| Classification | PRD class homeoboxes and pseudogenes |
| Havana BLAST/BLAT | OTTHUMG00000102171 |