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OTUB1 Antibody, Biotin Conjugated

OTUB1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, OTUB1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenOTUB1
SpecificityThis is a highly specific antibody against OTUB1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human OTUB1
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Due to its interaction with GRAIL, Expressed as two isoforms (one of which is present throughout the body and the other of which is present only in lymphoid tissues), OTUB1 functions as a hydrolase that can remove ubiquitin residues from target proteins, OTUB1 interacts with GRAIL and, OTUB1 is an important regulator of immune responses in secondary lymphoid organs, a phenomenon that occurs when T-cells are rendered unresponsive to their cognate antigens, plays a role in the regulation and the induction of T-cell anergy, thereby preventing protein degradation and playing an important role in protein turnover, via this interaction, OTUB1 is a 271 amino acid protein that contains one OTU (ovarian tumor) domain and belongs to the OTU family of predicted cysteine proteases
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FLJ20113 FLJ40710
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetOTUB1 Conjugated
Short name Conjugated, OTUB1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, OTUB1 (Antibody to)
Alternative techniqueantibodies
Identity 23077
Gene OTUB1
Long gene name OTU deubiquitinase, ubiquitin aldehyde binding 1
Synonyms gene name OTU domain, ubiquitin aldehyde binding 1
Locus 11q13, 1
Discovery year 2003-12-12
GenBank acession AY177200
Entrez gene record 55611
Pubmed identfication 12704427 19383985
RefSeq identity NM_017670
Classification OTU domain containing
Havana BLAST/BLAT OTTHUMG00000167786

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