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OTX1 + OTX2 Antibody, Cy5 Conjugated

OTX1 + OTX2 Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, OTX1 + OTX2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenOTX1 + OTX2
Specificity This has 79% sequence similarty with CRX, which is specific to Retinal tissue, This is a highly specific antibody against OTX1 + OTX2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range30-80/354
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human OTX1 + OTX2
Gene ID number 5013, 5015
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning, OTX1 and OTX2, OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, OTX1 is involved in corticogenesis, OTX2 is also required in the early specification of the neuroectoderm, The genes which encode OTX1 and OTX2 map to human chromosomes 2p13 and 14q21-q22, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism, are two murine homologs of the Drosophila orthodenticle (OTD), for the correct anterior neural plate specification and organization of the primitive streak, respectively, sensory organ development and pituitary functions, show a limited amino acid sequence divergence, specification and regionalization of the brain, which is destined to become the fore-midbrain, while OTX2 is necessary earlier in development, Transcription factors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetOTX1 + OTX2 Conjugated
Short name Conjugated, OTX1 + OTX2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, OTX1 and OTX2 (Antibody to)
Alternative techniqueantibodies
Identity 8522
Gene OTX2
Long gene name orthodenticle homeobox 2
Synonyms gene name orthodenticle homolog 2 (Drosophila)
Locus 14q22, 3
Discovery year 1994-02-08
GenBank acession AF298117
Entrez gene record 5015
Pubmed identfication 7959790
RefSeq identity , NM_021728
Classification PRD class homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000152338
Locus Specific Databases LOVD LRG_718

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