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OTX2 Antibody, Biotin Conjugated

OTX2 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, OTX2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenOTX2
SpecificityThis is a highly specific antibody against OTX2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human OTX2
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning, OTX1 and OTX2, OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, OTX1 is involved in corticogenesis, OTX2 is also required in the early specification of the neuroectoderm, The genes which encode OTX1 and OTX2 map to human chromosomes 2p13 and 14q21-q22, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism, are two murine homologs of the Drosophila orthodenticle (OTD), for the correct anterior neural plate specification and organization of the primitive streak, respectively, sensory organ development and pituitary functions, show a limited amino acid sequence divergence, specification and regionalization of the brain, which is destined to become the fore-midbrain, while OTX2 is necessary earlier in development, Transcription factors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetOTX2 Conjugated
Short name Conjugated, OTX2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, OTX2 (Antibody to)
Alternative techniqueantibodies
Identity 8522
Gene OTX2
Long gene name orthodenticle homeobox 2
Synonyms gene name orthodenticle homolog 2 (Drosophila)
Locus 14q22, 3
Discovery year 1994-02-08
GenBank acession AF298117
Entrez gene record 5015
Pubmed identfication 7959790
RefSeq identity , NM_021728
Classification PRD class homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000152338
Locus Specific Databases LOVD LRG_718

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